BENIGN TRANSIENT HYPERPHOSPHATASEMIA IN CHILDREN: TWELVE NEW CLINICAL CASES AND THE BIBLIOGRAPHICAL REVIEW

Q4 Medicine

Pediatriya - Zhurnal im G.N. Speranskogo Pub Date : 2023-02-17 DOI:10.24110/0031-403x-2023-102-1-165-170

E. Frolova, A. Anushenko, I. Shirokova, M. Venediktova, M. Varichkina, C.A. Kazakova

引用次数: 0

Abstract

Benign transient hyperphosphatasemia of childhood (TH, BTH, BTHC) is a condition characterized by a temporary significant increase in the level of alkaline phosphatase in healthy people. This condition is transient and it does resolve without treatment within 2 to 4 months, does not have any long-term consequences (according to the analysis of the bibliographical sources and the Authors’ own observations). BTH is most often detected in children under the age of 5 y/o with the peak under 2 years, however there are sporadic cases in adults observed. In addition, there are descriptions of familial cases of TH that are clinically identical to the sporadic ones. Authors present twelve own observations of BTH cases and the bibliographical review on the topic. The criteria for BTH diagnosing are formed and a benign course of this condition had been confirmed.

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儿童良性短暂性高磷酸酶血症:12例新临床病例及文献回顾

儿童期良性短暂性高磷酸血症(TH, BTH, BTHC)是一种以健康人群碱性磷酸酶水平暂时显著升高为特征的疾病。这种情况是暂时的，不经治疗可在2至4个月内消退，不产生任何长期后果(根据文献来源的分析和作者自己的观察)。BTH最常见于5岁以下儿童，2岁以下为高峰，但在成人中也有零星病例。此外，也有家族性TH病例的描述，临床上与散发性TH相同。作者提出了12个自己的观察BTH的情况下，并对该主题的书目审查。BTH的诊断标准已形成，并已确定为良性过程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatriya - Zhurnal im G.N. Speranskogo Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

150

期刊介绍： Journal “Pediatria” named after G.N. Speransky (the official short names of the Journal are “Journal «Pediatria»,” “Pediatria,” and “«Pediatria,» the Journal”) is the oldest Soviet-and-Russian (in the Russian Federation, the CIS and former Soviet Union) scientific and practical medical periodical assigned for pediatricians that is published continuously since May, 1922, and distributed worldwide. Our mission statement specifies that we aim to the ‘raising the level of skills and education of pediatricians, organizers of children’s health protection services, medicine scientists, lecturers and students of medical institutes for higher education, universities and colleges worldwide with an emphasis on Russian-speaking audience and specific, topical problems of children’s healthcare in Russia, the CIS, Baltic States and former Soviet Union Countries and their determination with the use of the World’s best practices in pediatrics.’ As part of this objective, the Editorial of the Journal «Pediatria» named after G.N. Speransky itself adopts a neutral position on issues treated within the Journal. The Journal serves to further academic discussions of topics, irrespective of their nature - whether religious, racial-, gender-based, environmental, ethical, political or other potentially or topically contentious subjects. The Journal is registered with the ISSN, - the international identifier for serials and other continuing resources, in the electronic and print world: ISSN 0031-403X (Print), and ISSN 1990-2182 (Online). The Journal was founded by the Academician, Dr. Georgiy Nestorovich SPERANSKY, in May, 1922. Now (since 1973) the Journal bears his honorary name.