Surgical oncology

J. Cassidy, D. Bissett, Roy A. J. Spence OBE, M. Payne, G. Morris-Stiff
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Abstract

Cancer is a disease of the genes. In the last two decades new technologies have allowed us to interrogate the genome more efficiently and faster. This has led to new therapies and improved understanding of cancers. It is clear the few cancers are caused by just one gene defect and in these rare cases the defective gene or its product is a target for therapeutic intervention. The bigger challenge now is to use this paradigm against multi-genic cancers which are far more common and more complex in their genetic makeup.
肿瘤外科
癌症是一种基因疾病。在过去的二十年里,新技术使我们能够更有效、更快速地研究基因组。这带来了新的治疗方法,提高了对癌症的了解。很明显,少数癌症是由一个基因缺陷引起的,在这些罕见的情况下,有缺陷的基因或其产物是治疗干预的目标。现在更大的挑战是使用这种模式来治疗多基因癌症,这些癌症在基因组成上更为常见和复杂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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