Evaluation of Ventilator Associated Respiratory Tract Infections (VARTI) by Common Anaerobic and Atypical Bacteria among the Patients of ICU of a Tertiary Care Hospital in Bangladesh

S. Alam, Taneem Mohammad, Moinul Hassan Chowdhury, M. Jamal, Abbasi Naser, Mohammad Ashrafuzzaman, S. Shamsuzzaman
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Abstract

Background and aim of the study:Ventilator-associated respiratory tract infection (VARTI)is theleading cause of higher mortalityand morbidity in ICU compared to non-ICU patients. Thisarticlereveals etiology of VARTI by commonanaerobic and atypical bacteria in ICU of Dhaka Medical College. Materials and Methodology: This is a cross-sectionalstudy where 200 endotracheal aspirate (ETA)samples were taken from clinically suspected patients of VARTI. After proper screening,bacteria were identified by PCR as because anaerobic and atypical bacteria cannot be easily grown inconventional culture media. Result: Sixty three (31.5%) samples were found to have VARTI. Among the common atypicalbacteriacausing, M. pneumoniae was found in 4 (6.35%) and L. pneumophila in 2 (3.17%) of the 63 samples. Insearch of the anaerobic bacteria causing VARTI,Peptostreptococcus was detected in 3 (4.76%) whileFusobacterium nucleatum andPrevotella melaninogenicawere detected in 2 (3.17%) each of the 63 samples. Conclusion: Anaerobic and atypical bacteria are implicated in VARTI in ICU although at a relative lowrate. JBSA 2021; 34(1): 32-37
孟加拉国某三级医院ICU患者常见厌氧细菌和非典型细菌对呼吸机相关呼吸道感染(VARTI)的评价
研究背景和目的:与非ICU患者相比,呼吸机相关呼吸道感染(VARTI)是ICU患者死亡率和发病率较高的主要原因。本文探讨了达卡医学院ICU常见厌氧菌和非典型细菌引起VARTI的病因。材料和方法:这是一项横断面研究,从临床疑似VARTI患者中提取200份气管内吸入(ETA)样本。经适当筛选后,通过PCR鉴定出细菌,因为厌氧和非典型细菌在常规培养基中不易生长。结果:63例(31.5%)标本有VARTI。在常见的非典型致病菌中,肺炎支原体4例(6.35%),嗜肺乳杆菌2例(3.17%)。63份样本中检出3株(4.76%)为胃链球菌,2株(3.17%)为核efusobacterium nucleatum, 2株(3.17%)为产黑素普雷沃菌。结论:厌氧细菌和非典型细菌与ICU VARTI有关,但发生率相对较低。JBSA 2021;34 (1): 32-37
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