Characteristics of Adult Celiac Disease in Eastern Algeria

Journal of Biomedical and Clinical Research Pub Date : 2023-06-01 DOI:10.2478/jbcr-2023-0003

Nousseiba Abed, Imen Bouzaroura, Amel Guergour

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Abstract

Summary The objective of this study was to determine the clinical picture of adult celiac disease in the population of eastern Algeria. We conducted a retrospective study on a sample of 156 patients in Internal Medicine service, Hepato-Gastroenterology Service, Endoscopy Service in the University Hospital BENBADIS - Constantine and the Military Regional University Hospital - Constantine. Our results have shown that, in this population, celiac disease can be manifested by a number of signs and related pathologies. A variety of digestive symptoms were reported, primarily chronic diarrhea (81.4%), abdominal pain (57.1%), anorexia (42.9%) and vomiting (48%). Extra-digestive symptoms manifested mainly as weight loss (90.4%), pallorous of skin and mucosa (84%), asthenia (60,3%), edema of the lower limbs (46.8%) and dehydration sings (37.8%). In addition, we noted biological disorders, the most common being hypocalcemia (77.4%) and hypoalbuminemia (57.7%), and a series associated pathologies namely: anemia (67.9%) and digestive diseases (38.46%). CD in adults in our population may express a variety of digestive and extra-digestive symptoms in addition to a number of associated pathologies.

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阿尔及利亚东部成人乳糜泻的特点

本研究的目的是确定阿尔及利亚东部人群中成人乳糜泻的临床表现。我们对康斯坦丁本巴迪斯大学医院和康斯坦丁军区大学医院内科、肝消化科、内窥镜科的156例患者进行了回顾性研究。我们的研究结果表明，在这个人群中，乳糜泻可以表现为一些体征和相关病理。报告了多种消化系统症状，主要是慢性腹泻(81.4%)、腹痛(57.1%)、厌食(42.9%)和呕吐(48%)。消化系统外症状主要表现为体重减轻(90.4%)、皮肤黏膜苍白(84%)、虚弱(60.3%)、下肢水肿(46.8%)和脱水(37.8%)。此外，我们注意到生物性疾病，最常见的是低钙血症(77.4%)和低白蛋白血症(57.7%)，以及一系列相关病理，即贫血(67.9%)和消化系统疾病(38.46%)。在我们的人群中，成人乳糜泻除了一些相关的病理外，还可能表现出各种消化和消化外症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Biomedical and Clinical Research

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