CT features, Pathological findings and Clinical data of Follicular Dendritic Cell Sarcoma in the Mediastinum: Case Report and Literature Review

Abstract

Follicular dendritic cell sarcoma (FDC sarcoma) is an uncommon neoplasm with few reported cases. We investigated the Computed Tomography (CT) appearance and pathological findings in a 43years-old lady diagnosed with mediastinal FDC sarcoma using pathological tests. It's usually confused with lymphoma. The literature was reviewed for previous FDC sarcoma reports. FDC sarcoma should be considered in asymptomatic patients with mediastinal lymph node lesions with a diameter of more than 1 cm and appear as an ill-defined mass with an arborizing pattern of necrosis. CD21(+) is a specific immunohistochemically marker for determining the pathological diagnosis of FDC sarcoma.