The role of mitochondria in tumorigenesis

Abstract

The maternal inheritance of the mitochondrial DNA is one of its amazing characteristics. It is located in the matrix of a mitochondrion. The cellular organelle that is responsible for the generation of ATPs is the mitochondrion. A lot of studies have linked the mitochondria with the generation of cancer cells. There is a crosstalk in the medical research field that whether the cancer cells were originated from a nuclear defect or from a mitochondrial dysfunction. In this review paper, I will highlight the role of mitochondria in tumorigenesis.