{"title":"The genetics of type 2 diabetes: the consequences of complexity","authors":"Mark McCarthy","doi":"10.1046/j.1466-9218.2000.00017.x","DOIUrl":null,"url":null,"abstract":"<p>Type 2 diabetes affects a significant proportion of the World’s population and shows strong familial association. A richer molecular understanding of the aetiological mechanisms is a prerequisite for the development of improved therapeutic and preventative options to ameliorate the burden of disease. The genome-scale analyses now possible should allow the major susceptibility genes for type 2 diabetes to be identified, provided due respect is paid to the inevitable complexities associated with the genetic analysis of multifactorial traits.</p>","PeriodicalId":100575,"journal":{"name":"GeneScreen","volume":"1 2","pages":"81-84"},"PeriodicalIF":0.0000,"publicationDate":"2008-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1466-9218.2000.00017.x","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"GeneScreen","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1046/j.1466-9218.2000.00017.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Type 2 diabetes affects a significant proportion of the World’s population and shows strong familial association. A richer molecular understanding of the aetiological mechanisms is a prerequisite for the development of improved therapeutic and preventative options to ameliorate the burden of disease. The genome-scale analyses now possible should allow the major susceptibility genes for type 2 diabetes to be identified, provided due respect is paid to the inevitable complexities associated with the genetic analysis of multifactorial traits.
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