Neonate born with ischemic limb to a COVID-19 positive mother: management and review of literature

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Case Reports in Perinatal Medicine Pub Date : 2020-12-09 DOI:10.1515/crpm-2020-0086

S. Perveen, K. Millington, S. Acharya, A. Garg, Vita Boyar

引用次数: 8

Abstract

Abstract Objectives To describe challenges in diagnosis and treatment of congenital neonatal gangrene lesions associated with history of maternal coronavirus disease 2019 (COVID-19) infection. Case presentation A preterm neonate was born with upper extremity necrotic lesions and a history of active maternal COVID-19 infection. The etiology of his injury was challenging to deduce, despite extensive hypercoagulability work-up and biopsy of the lesion. Management, including partial forearm salvage and hand amputation is described. Conclusions Neonatal gangrene has various etiologies, including compartment syndrome and intrauterine thromboembolic phenomena. Maternal COVID-19 can cause intrauterine thrombotic events and need to be considered in a differential diagnosis.

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COVID-19阳性母亲新生儿肢体缺血:处理及文献回顾

摘要目的探讨与母体冠状病毒病2019 (COVID-19)感染史相关的新生儿先天性坏疽病变的诊断和治疗挑战。1例早产新生儿出生时伴有上肢坏死病变，并有母体活动性COVID-19感染史。尽管对病变进行了广泛的高凝检查和活检，但他受伤的病因仍难以推断。管理，包括部分前臂抢救和手部截肢的描述。结论新生儿坏疽有多种病因，包括腔室综合征和宫内血栓栓塞现象。母体COVID-19可引起宫内血栓形成事件，需要在鉴别诊断中予以考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Perinatal Medicine OBSTETRICS & GYNECOLOGY-

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期刊介绍： Case Reports in Perinatal Medicine is a double-blind peer-reviewed journal. The objective of the new journal is very similar to that of JPM. In addition to evidence-based studies, practitioners in clinical practice esteem especially exemplary reports of cases that reveal specific manifestations of diseases, its progress or its treatment. We consider case reports and series to be brief reports describing an isolated clinical case or a small number of cases. They may describe new or uncommon diagnoses, unusual outcomes or prognosis, new or infrequently used therapies and side effects of therapy not usually discovered in clinical trials. They represent the basic concept of experiences for studies on representative groups for further evidence-based research. The potential roles of case reports and case series are: Recognition and description of new diseases Detection of drug side effects (adverse or beneficial) Study of mechanisms of disease Medical education and audit Recognition of rare manifestations of disease.