Studying Several Virulence Factors Phenotypically and Genetically to Isolate Klebsiella Pneumonia from Diabetic Patients

Abstract

Klebsiella pneumoniae is the most frequent cause of nosocomial and community-acquired infections. The virulence factors help Klebsiella pneumoniae establish an infection in the human body by contributing to its ability to survive in a variety of environmental circumstances. 42 K. pneumoniae clinical specimens were isolated from diabetic patients suffering from urinary tract infection and diabetic foot ulcer in this study. K.pneumoniae virulence factors are currently being identified using phenotypic and genotypic approaches. The K. pneumoniae isolates that were positive for several virulence factors included 33 (78.6%) capsule, 17 (40%) hypermucoviscosity development, 14 (33.3%) proteases, and none were positive for hemolysis . K. pneumoniae isolates had a virulence gene that was 15% wcaG, 60% entB, and negative for rmpA.