ChemInform Abstract: Oxidative Rearrangement Strategy for Synthesis of 2,4,5-Trisubstituted Oxazoles Utilizing Hypervalent Iodine Reagent.

ChemInform Pub Date : 2016-12-06 DOI:10.1002/chin.201652253
Qing Liu, Xiaohui Zhang, Yang He, Muhammad Ijaz Hussain, Wen Hu, Yan Xiong, Xiangming Zhu
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引用次数: 0

Abstract

Trisubstituted oxazoles (II) are directly synthesized from 3-hydroxybut-2-enimidates (I) through oxidative rearrangement strategy using diacetoxyiodobenzene as oxidizing agent under mild conditions.

摘要:利用高价碘试剂合成2,4,5-三取代恶唑的氧化重排策略。
以二乙酰氧基碘苯为氧化剂,在温和条件下由3-羟基丁-2-邻苯二甲酸酯(I)经氧化重排直接合成三取代恶唑(II)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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