Medicinal effects of Propolis diet on biochemicals and histological factors in rats

Mahdi Bayrami, M. Khakpoor, E. Safavi, A. Bayrami
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引用次数: 2

Abstract

Background/aim: There is increasing interest in the healing potential of natural products, such as Propolis, considering the availability and low cost of these products. The present study was conducted to evaluate biochemical and histological effects of ethanol extract of Propolis (EEP) on intestinal tissue in rats. Materials and methods: Healthy Wistar rats were indiscriminately assigned into three groups (A-C) and five rats in each. The group A were orally given 0.2 mL of dimethyl sulfoxide daily as a control, while rats in Groups B and C were administered the same 0.2 mL dimethyl sulfoxide containing 300 and 600 mg/kg body weight ethanol extract of bee Propolis for 21 days respectively. Results: It has been concluded that ethanol extract of Propolis significantly increases globulin levels in group 300 mg/kg ( p <0.05). It also, significantly increases the height of the villi, the of the mucous membrane and muscles in the group 600 mg/kg ( p <0.05). Conclusion: It could be concluded from the present investigation that the Propolis has positive effect on animal hygiene by increasing the immunity and decreasing the stress via increase the globulin level in the blood, but the beneficial effect of Propolis seems to be dose dependent.
蜂胶日粮对大鼠生化及组织学因子的影响
背景/目的:考虑到蜂胶等天然产品的可获得性和低成本,人们对蜂胶等天然产品的治疗潜力越来越感兴趣。本研究旨在探讨蜂胶乙醇提取物(EEP)对大鼠肠道组织的生化和组织学影响。材料与方法:将健康Wistar大鼠随机分为3组(A-C),每组5只。A组大鼠每天口服二甲亚砜0.2 mL作为对照,B组和C组大鼠分别给予含有300和600 mg/kg体重蜂胶乙醇提取物的二甲亚砜0.2 mL,连续21 d。结果:蜂胶乙醇提取物显著提高了300 mg/kg组仔猪球蛋白水平(p <0.05)。600 mg/kg组绒毛高度、黏膜高度和肌肉高度均显著升高(p <0.05)。结论:蜂胶通过提高血液中球蛋白水平,提高机体免疫力,降低应激,对动物卫生具有积极作用,但蜂胶的有益作用似乎是剂量依赖性的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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