Encapsulation of a bioactive steroid in apolymer matrix

A. Collado, G. Hernandez, V. Morejon, F. Coll, C. Peniche
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Abstract

DI-31 is a synthetic analog of brasinosteroids (ABR), the active ingredient (PA) of Biobras, a plantgrowth stimulant, which has shown positive impact on Cuban agriculture, especially in rice cultivation. However, ithas the drawback of having low solubility in water and being rapidly metabolized by the plants. An alternative toovercome these limitations is its micro-encapsulation in a polymer matrix. Chitosan (CHI) has been investigatedas an excellent candidate for microencapsulation of DI-31. Chitosan (CHI) is a natural polysaccharide obtainedfrom chitin extracted from exoesqueleton of crustaceans, which increases resistance of the plants to the attack ofpests and promotes the yield of the crops, also possesses excellent biocompatibility, biodegradability andmucoadhesivity, also inducing the defense of the plants against the attack of different pathogens. # polymer_matrix #chitosan #microparticles #spray_drying #DI-31
生物活性类固醇在聚合物基质中的包封
DI-31是brasinosteroids (ABR)的合成类似物,ABR是一种植物生长刺激剂Biobras的活性成分(PA),对古巴农业,特别是水稻种植产生了积极影响。然而,它的缺点是在水中溶解度低,被植物迅速代谢。克服这些限制的另一种方法是将其微封装在聚合物基质中。壳聚糖(CHI)被认为是DI-31微胶囊化的理想候选材料。壳聚糖(CHI)是从甲壳类动物外皮中提取的几丁质中提取出来的一种天然多糖,它能提高植物对害虫的抵抗力,提高作物的产量,还具有良好的生物相容性、可生物降解性和黏附性,诱导植物防御不同病原体的侵袭。#聚合基质#壳聚糖#微粒#喷雾干燥#DI-31
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