Research status and progress of Glypican-3 and liver carcinoma

Q4 Health Professions

中华检验医学杂志 Pub Date : 2020-02-11 DOI:10.3760/CMA.J.ISSN.1009-9158.2020.02.018

M. Dong, Qi Li, Xiang-xiang Liu

引用次数: 0

Abstract

Phosphatidylinositol protein 3 (Glypican-3, GPC3) is a cell-surface heparan sulfate proteoglycan that belongs to the glycine related global membrane proteoglycan relatives.Many studies have shown that it is of great significance in the occurrence, diagnosis, treatment and prognosis of hepatocellular carcinoma (HCC).This paper reviews the recent studies on GPC3. Key words: Liver neoplasms; Glypicans; Biomarkers, tumor; Prognosis

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Glypican-3与肝癌的研究现状与进展

磷脂酰肌醇蛋白3 (Glypican-3, GPC3)是一种细胞表面硫酸肝素蛋白聚糖，属于甘氨酸相关的全局膜蛋白聚糖亲戚。许多研究表明，它对肝细胞癌(HCC)的发生、诊断、治疗和预后具有重要意义。本文综述了近年来GPC3的研究进展。关键词:肝脏肿瘤;Glypicans;肿瘤生物标志物;预后

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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