Frequency of SCF Leakage in Post-operative Patients of Tethered Spinal Cord in A Tertiary Care Hospital

M. A. Rehman, Junaid Aziz, Inamullah Asghar, T. Anwar, Anum Wahab, Muhammad Akmal Hussain
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Abstract

Objective:  The study aimed to report the incidence of CSF leakage in patients with a tethered spinal cord, post-operatively. Materials and Methods:  A total of 75 individuals aged more than 2 years and of either gender who were hospitalized for surgery for tethered cord syndrome were included. All patients had a preoperative MRI of the spine, and those above the age of 6 had urodynamic tests. Clinical evaluations were performed until hospital release, then again at 3, 6, and 12 months. Urodynamic tests and spine MRIs were redone one year following surgery. Under general anesthesia, all patients had microscopic untethering procedures to release tethering materials and heal the thecal sac. Results:  52% of patients fall under TCS type ‘simple’, whereas, 48% of patients found with complex TCS. The frequency of CSF leakage in post-operative patients with a tethered spinal cord was found in 17.33%. No CSF leak was reported in the majority of patients (49%) patients in the age group 2-30 years. 52% of patients with simple TCS reported no CSF leak, whereas, only 13(18%) patients with complex TCS reported CSF leaks. 40% of patients reported no CSF leak who was diagnosed with complex TCS. There existed a significant relationship between the types of TCS (simple/complex) for CSF leak distribution. Conclusion:  This study concluded that the frequency of CSF leakage in post-operative patients with tethered spinal cord was found in 17.33% of patients. Keywords:  Tethered Spinal Cord (TCS), CSF Leakage, Lipomyelomeningocele.
某三级医院脊髓栓系术后患者SCF渗漏的发生率
目的:本研究旨在报道脊髓栓系患者术后脑脊液漏的发生率。材料和方法:共纳入75例2岁以上因脊髓栓系综合征住院手术的患者,不论男女。所有患者术前均行脊柱MRI检查,6岁以上患者行尿动力学检查。在出院前进行临床评估,然后在第3、6和12个月时再次进行评估。术后一年复查尿动力学检查和脊柱mri。在全身麻醉下,所有患者都进行了显微解栓手术,以释放系栓材料并愈合鞘囊。结果:52%的患者属于“简单”型TCS,而48%的患者属于复杂TCS。脊髓栓系术后脑脊液漏发生率为17.33%。在2-30岁年龄组中,大多数患者(49%)未报告脑脊液泄漏。52%的单纯性TCS患者报告无脑脊液泄漏,而只有13例(18%)的复杂TCS患者报告脑脊液泄漏。40%诊断为复杂TCS的患者报告无脑脊液泄漏。脑脊液渗漏分布与TCS类型(简单/复杂)有显著关系。结论:脊髓栓系术后脑脊液漏发生率为17.33%。关键词:脊髓栓系,脑脊液漏,脂质脊膜膨出。
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