A comparison of the relative effectiveness of intravenous patient controlled-analgesia delivered morphine and morphine with fentanyl

Pain Clinic Pub Date : 2006-07-01 DOI:10.1163/156856906778026149

K. Lin, W. Chou, Cheng-Huang Wang, A. Concejero, Chien-Hui Yang, K. Cheng, Chia-Jung Huang, Chih-Shien Wang, Kuan-Hung Chen, K. Chang, B. Jawan

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Abstract

AbstractThe aim of this study is to compare the effectiveness of intravenous patient-controlled analgesia using morphine with fentanyl and morphine alone in patients undergoing gynecologic surgery. A retrospective analysis of the pain control charts of 204 patients was performed. Forty-one patients received morphine with fentanyl (GI) and 163 patients received only morphine (GII). The patients were evaluated twice each day. The degree of pain relief was assessed using a visual analogue scale (VAS). The doses used and analgesic drug-related complications including adverse effects were noted. The VAS scores in GI from postoperative days 1–3 were 2.8 ± 0.8, 1.8 ± 0.7, and 1.3 ± 0.5, respectively, and the VAS scores in GII from postoperative days 1–3 were 3.1 ± 0.9, 2.3 ± 0.8, and 1.9 ± 0.7, respectively. The difference in VAS scores between the two groups was statistically significant. The mean total dose of morphine consumed was 29.4 ± 11.6 mg in GI and 39.7 ± 33.2 mg in GII. There was no statistically sign...

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静脉注射吗啡与吗啡加芬太尼镇痛的相对疗效比较

摘要本研究的目的是比较芬太尼和吗啡单独应用于妇科手术患者静脉自控镇痛的效果。对204例患者的疼痛控制图进行回顾性分析。41例患者接受吗啡加芬太尼治疗(GI)， 163例患者仅接受吗啡治疗(GII)。每天对患者进行两次评估。采用视觉模拟量表(VAS)评估疼痛缓解程度。记录了使用的剂量和镇痛药物相关并发症，包括不良反应。术后1 ~ 3 d GI VAS评分分别为2.8±0.8、1.8±0.7、1.3±0.5，术后1 ~ 3 d GII VAS评分分别为3.1±0.9、2.3±0.8、1.9±0.7。两组患者VAS评分差异有统计学意义。GI组和GII组吗啡平均总剂量分别为29.4±11.6 mg和39.7±33.2 mg。没有统计学上的迹象……

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Pain Clinic

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