The characteristics of bilateral breast cancer patients

Q4 Medicine

Nowotwory Pub Date : 2018-01-01 DOI:10.5603/2018.0035

B. Sas-Korczyńska, Wojciech Kamzol, M. Kołodziej-Rzepa, J. Mituś, W. Wysocki

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引用次数: 1

Abstract

Introduction. Bilateral breast cancer (BBC) consists of 2–12% all cases of breast carcinoma. In relation to time between the first and second cancer diagnosis, the synchronous (s-BBC) or metachronous (m-BBC) bilateral breast cancer is defined. Material and methods. The clinicopathologic characteristics of 303 patients treated between 1963 and 2014 for bilateral breast cancer was presented. Synchronous BBC was diagnosed in 70 patients (23.1%) and remaining 233 patients (76.9%) developed metachronous BBC. Patients with m-BBC in comparison to s-BBC were younger (mean age: 51.4 vs 60.6 years), the positive family cancer history was rare (36.7% vs 48.5%), and more frequently these patients were before menopause (65.7% vs 44.3%). While the lobular type of breast cancer which consisted of 6.6% cases in first breast and 8.9% cases of second carcinomas, more frequently was presented in s-BBC (8.6%) in comparison to m-BBC (6%). Results. The mean time of follow up was 174 months. The 5- and 10-year overall survival rates were 89.3% and 76.1%, respectively. The presence of s-BBC connected with worse prognosis; the 5- and 10-year overall survival were 93.1% and 82% for m-BBC and 76.4% and 52.1% for s-BBC (p = 0.00244, log-rank test).

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双侧乳腺癌患者的特点

介绍。双侧乳腺癌(BBC)占所有乳腺癌病例的2-12%。根据第一次和第二次癌症诊断之间的时间，定义了同步(s-BBC)或异时(m-BBC)双侧乳腺癌。材料和方法。报告1963 - 2014年间303例双侧乳腺癌患者的临床病理特点。同步BBC 70例(23.1%)，异时BBC 233例(76.9%)。与s-BBC相比，m-BBC患者更年轻(平均年龄:51.4岁vs 60.6岁)，阳性家族史罕见(36.7% vs 48.5%)，绝经前患者更常见(65.7% vs 44.3%)。小叶型乳腺癌在第一乳房中占6.6%，在第二乳房中占8.9%，但s型bbc(8.6%)比m型bbc(6%)更常见。结果。平均随访时间为174个月。5年和10年总生存率分别为89.3%和76.1%。s-BBC的存在与预后较差有关;m-BBC的5年和10年总生存率分别为93.1%和82%，s-BBC的5年和10年总生存率分别为76.4%和52.1% (p = 0.00244, log-rank检验)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nowotwory Medicine-Oncology

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： NOWOTWORY Journal of Oncology publishes papers which cover all aspects of oncology but concentrates on clinical studies, both research orientated and treatment orientated, rather than on laboratory studies. Contributions are also welcomed from the fields of epidemiology, tumor pathology, radiobiology and radiation physics.