Plasma Proteins in Enterica Serovar Typhi patients in Northern Sudan

Abstract

Background: The study entailed a quantitative assessment of serum total protein, albumin, globulin, and albumin. Method: globulin ratio in individuals who diagnosed positively with typhoid fever and detection any alteration in plasma protein in receptiveness to typhoid titers. One hundred positively diagnosed with typhoid infection mean age (41.5 ± 2.1) years on zero day treatments. In addition to healthy one hundred individuals mean age (42.9 ± 1.9) years were recruited in this study. Results: There were significant difference  P. value = 0.000   in total protein, serum albumin, serum globulin and A/G ratio for typhoid positive and negative,  mean (8.4±0.01,6.8±0.06), (3.5±0.01, 4.1±0.03), (4.9±0.01, 2.8±0.06), (0.7 ± 0.003, 1.5 ± 0.02) respectively. No significant difference, P. value was 0.632, 0.832 and 0.760 serum total protein (7.5 ± 0.92, 7.6 ± 0.79) serum albumin (3.8 ± 0.38, 3.8 ± 0.37) and serum globulin (3.8 ± 0.16, 3.9 ± 0.16) for males and females respectively. Also no significant difference, P. value was 0.11, 0.60, and 0.06 serum total protein (8.4 ± 0.01, 8.4± 0.02) serum albumin (3.5 ± 0.01, 3.5 ± 0.01) and serum globulin (5.0 ± 0.01, 4.9 ± 0.01) for titer 1/160 and titer 1/320. Conclusion: Low albumin level and hypoglycemia should be surveillant when anti typhoid pharmaceutical commenced. Key words: Plasma Proteins, Enterica Serovar Typhi, Sudan