Pregnancy outcomes in women with systemic lupus erythematosus.

Abstract

Objective : The purpose of this study was to examine pregnancy outcomes in women with systemic lupus erythematosus (SLE). Study design : Data from the California Health Information for Policy Project, which links records from birth certificates and hospital discharge records of mothers and newborns who delivered in all civilian hospitals in the state of California between 1 January 1993 and 31 December 1994, were retrospectively reviewed. Patients with a singleton gestation were stratified into the study group if they had a diagnosis of SLE, based on the International Classification of Disease, 9th Revision, or into the control group if they did not have SLE and delivered during the interval from 1 January 1994 to 31 December 1994. Specific maternal outcomes including pregnancy complications and fetal and neonatal outcomes were assessed and compared between the two groups. Results : During the 2-year study period, 555 women had a diagnosis of SLE, and approximately 600 000 women were included in the contr...