І. Dron, N. Bukartyk, M. Bukartyk, D. Ostapiv, V. Samaryk
{"title":"PREPARATION OF ANTISEPTIC HYDROGEL PLATES BASED ON NATURAL POLYSACCHARIDES","authors":"І. Dron, N. Bukartyk, M. Bukartyk, D. Ostapiv, V. Samaryk","doi":"10.23939/ctas2022.02.178","DOIUrl":null,"url":null,"abstract":"Using natural polysaccharides, pectin and sodium alginate, hydrogel plates capable of absorbing exudate were obtained. Studies have shown no cytotoxicity of the plate material. In order to create bactericidal therapeutic dressings based on them, the possibility of filling the plates with antiseptics (iodine, betadine, chlorhexidine) was shown and their release dynamics was studied. Studies have shown that the release of iodine from the plate is too fast and can not meet the condition of its prolonged release in contrast to betadine and chlorhexidine.","PeriodicalId":9808,"journal":{"name":"Chemistry, Technology and Application of Substances","volume":"13 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry, Technology and Application of Substances","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23939/ctas2022.02.178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Using natural polysaccharides, pectin and sodium alginate, hydrogel plates capable of absorbing exudate were obtained. Studies have shown no cytotoxicity of the plate material. In order to create bactericidal therapeutic dressings based on them, the possibility of filling the plates with antiseptics (iodine, betadine, chlorhexidine) was shown and their release dynamics was studied. Studies have shown that the release of iodine from the plate is too fast and can not meet the condition of its prolonged release in contrast to betadine and chlorhexidine.