Benign chondroid syringoma of foot: a clinical dilemma

Abstract

of epithelial cells were also apparent. Cellular pleomorphism was absent (Figure 4). These histopathological findings pointed towards the final diagnosis of a benign chondroid syringoma (eccrine type) of the left foot. Immunohistochemistry (IHC) was also performed, which revealed a strong positivity of inner epithelial layer for cytokeratin (CK) 7 as well as epithelial membrane antigen (EMA) and the outer myoepithelial layer for vimentin, S100 and p63. A negative immunoexpression of tumor cells for p15, p16 and desmin was seen. The post-operative period of the patient was uneventful. There was no evidence of recurrence of the lesion during her 2 year follow-up period. Abstract Chondroid syringoma is a rare skin appendageal tumor which is most commonly encountered in the head and neck region. We herein report an unusual case of a benign chondroid syringoma of the left foot in a 40-year-old female which posed as a diagnostic conundrum. The approach to such a case, differential diagnosis and the management of this rare entity is also presented.