Infrared Analysis of Pharmaceuticals II*

Abstract

In the course of an investigation into the applicability of a quantitative potassium bromide disk method to various drugs and chemicals, the cinchona alkaloids, quinidine, quinine, cinchonine, and cinchonidine were studied. Under certain experimental conditions, possibly due to the formation of dimorphous and amorphous forms, anomalous spectra were obtained for quinidine and quinine. Cinchonine and cinchonidine did not exhibit significant variations in spectra under the conditions investigated.