Detection of Human Tumor Markers with THz Metamaterials

C. Weisenstein, D. Schaar, M. Schmeck, A. Wigger, Anja Bosserhoff, P. Bolívar
{"title":"Detection of Human Tumor Markers with THz Metamaterials","authors":"C. Weisenstein, D. Schaar, M. Schmeck, A. Wigger, Anja Bosserhoff, P. Bolívar","doi":"10.1109/IRMMW-THZ.2018.8510052","DOIUrl":null,"url":null,"abstract":"THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.","PeriodicalId":6653,"journal":{"name":"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)","volume":"18 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IRMMW-THZ.2018.8510052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

Abstract

THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.
太赫兹超材料检测人类肿瘤标志物
太赫兹生物分析技术已经被证明是一种可行的无标记检测生物分子的工具。但是,太赫兹传感技术要达到与应用相关的灵敏度水平,还需要进行重大改进。我们提出了使用高度敏感的超材料基太赫兹生物传感器对人类肿瘤标志物进行无标记太赫兹传感。利用特异性蛋白与DNA的高亲和力结合进行定位功能化,进一步提高检测灵敏度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信