Transmission Imaging in a PET Scanner Based on Forward-Scattered 662-keV Photons

J. Hamill, M. Teimoorisichani
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Abstract

The use of LSO background radiation (gamma rays from naturally occurring 176Lu) has been studied in the past as a means of generating a PET attenuation map without CT. However, the low flux of background radiation has fundamentally limited this approach, requiring a long scanning time. In this work, a different approach is proposed, increasing the flux of gamma rays and thereby shortening the required scanning time. The proposed method is based on the principle of 137CS sources positioned behind the PET detectors. In this method, 662-ke V photons from the sources can enter the detectors and scatter in a forward direction across the scanner's field of view. Although multiple sources could be used, the proposed method was tested with a single 115 MBq 137CS source. A 6-ring Biograph Vision PET/CT scanner with LSO scintillators and SiPM -based detectors was used. Two-dimensional energy histograms were derived from list-mode PET events and so were sinograms, including blank scans with nothing in the field of view and a transmission scan with the patient bed in the field of view. Energy histograms showed the forward-scattered coincidence events. A transmission sinogram of the bed was created as the ratio of the transmission and blank sinograms. A method was introduced to estimate the sensitivity gain, compared to the LSO background method, of a proposed configuration with 38 137CS sources. The estimated gain was 6.5 in the case of 30 MBq per source, leading to the prediction that transmission scan times could be 6.5 times faster.
基于前向散射662 kev光子的PET扫描仪透射成像
过去曾研究过使用LSO背景辐射(自然产生的176Lu的伽马射线)作为产生PET衰减图的手段,而不使用CT。然而,背景辐射的低通量从根本上限制了这种方法,需要很长的扫描时间。在这项工作中,提出了一种不同的方法,增加伽马射线的通量,从而缩短所需的扫描时间。提出的方法是基于137CS源定位在PET探测器后面的原理。在这种方法中,来自源的662克V光子可以进入探测器,并在扫描仪的视野中向前散射。虽然可以使用多个源,但所提出的方法在单个115 MBq 137CS源上进行了测试。使用6环Biograph Vision PET/CT扫描仪,带有LSO闪烁体和基于SiPM的检测器。二维能量直方图是由列表模式PET事件得出的,正弦图也是如此,包括视场中没有任何内容的空白扫描和视场中有病床的透射扫描。能量直方图显示了前向散射的巧合事件。将透射正弦图与空白正弦图的比值作为床层的透射正弦图。与LSO背景法相比,介绍了一种估计具有38个137CS源的结构灵敏度增益的方法。在每个源30 MBq的情况下,估计增益为6.5,从而预测传输扫描时间可能会快6.5倍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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