Ultrasound features of placental changes and their obstetric correlates among HIV patients and controls at Aminu Kano Teaching Hospital, Kano

A. Rabiu, A. Ismail, Y. Lawal, J. Mu'uta
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Abstract

Background: One of the serious health problems in the world today is the human immunodeficiency virus (HIV)/acquired immune deficiency syndrome pandemic, with Nigeria having the second largest number of new cases. During pregnancy, HIV-infected women face more adverse effects than uninfected women. This study aimed at evaluating ultrasound features of placentas of HIV-positive women and controls to demonstrate a difference in vasculoplacental complications between the two groups. Methods: A comparative study was conducted among HIV-positive women and their matched controls. Informed consent was obtained and a pretested interviewer-administered questionnaire was used. The women had ultrasound assessment of the placenta and an obstetric ultrasound scan. Results: There were no differences in placental surface area (t = −1.122, df = 6, P = 0.305, 95% confidence interval: −17.46 to 15.56) and placental thickness (t = 1.846, df = 58, P = 0.07, 95% confidence interval: −0.405 to 9.99). Calcifications were found but not related to HIV status. The most common complication among the HIV-infected women was miscarriage. No complications were recorded among the controls. Conclusion: There was no difference in the vasculopathological changes detectable by ultrasound scan in the placentas of HIV-infected and uninfected pregnant women.
卡诺Aminu Kano教学医院HIV患者和对照组胎盘变化的超声特征及其产科相关性
背景:当今世界严重的健康问题之一是人体免疫机能丧失病毒(艾滋病毒)/获得性免疫机能丧失综合症大流行,尼日利亚是新病例数量第二多的国家。在怀孕期间,感染艾滋病毒的妇女比未感染的妇女面临更多的不利影响。本研究旨在评估hiv阳性妇女和对照组胎盘的超声特征,以证明两组之间血管胎盘并发症的差异。方法:对hiv阳性妇女与对照组进行比较研究。获得知情同意,并使用预先测试的访谈者管理的问卷。这些妇女进行了胎盘超声评估和产科超声扫描。结果:两组胎盘表面积(t = - 1.122, df = 6, P = 0.305, 95%可信区间:- 17.46 ~ 15.56)和胎盘厚度(t = 1.846, df = 58, P = 0.07, 95%可信区间:- 0.405 ~ 9.99)差异无统计学意义。发现钙化,但与HIV状态无关。感染艾滋病毒的妇女中最常见的并发症是流产。对照组无并发症发生。结论:hiv感染与未感染孕妇胎盘超声检查血管病理变化无明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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