Sequencing Analysis of Hepatitis

J. Varela
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Abstract

Hepatitis B Virus (HBV) could also be a noncytopathic DNA virus that infects approximately 350 million people worldwide and should be a number one explanation for liver cirrhosis and hepatoma. The evolutionary dynamics of HBV are characterized by high mutation rates due to the error-prone polymerase (RT) and rapid replication rates. Thus, an outsized number of viral variants are constantly generated, creating great genetic diversity on which survival operates.
肝炎病毒序列分析
乙型肝炎病毒(HBV)也可能是一种非细胞病变DNA病毒,感染了全世界约3.5亿人,应该是肝硬化和肝癌的头号原因。HBV进化动力学的特点是由于容易出错的聚合酶(RT)和快速复制率而导致高突变率。因此,大量的病毒变体不断产生,创造了巨大的遗传多样性,使生存得以维持。
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