Sperm dna bridges versus genetic variability: an editorial

Abstract

Sperm DNA fragmentation is recognized to compromise male fertility. The data entail that sperm DNA damage can be competently treated with oral antioxidant administration during a comparatively short time period. It is an understanding that the 2 types of DNA appear to be different and autonomously packaged molecules; though, research has demonstrated the interdependent nature of these conformations in contributing to male infertility. Data must endure to be congregated to establish strong associations between traditional semen analysis parameters and sperm DNA integrity; this information remnants controversial and useless in clinical practice until novel techniques for the diagnosis and treatment of sperm DNA can be established. More modern technology must be employed to correlate such information into valuable clinical awareness. This editorial is the collation of reports relating to research on sperm DNA biochemistry and molecular biology to establish an opinion revealing sperm DNA integrity likely to be both tremendously fragile and remarkably significant for male fertility.