Pitfalls in dermatopathology: when things are not what they seem

Taylor Deal, V. Mishra, B. Duong, A. Andea
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引用次数: 5

Abstract

By integrating the clinical features of a skin lesion and its histological findings, dermatopathologists are usually able to correctly diagnose most skin disorders. However, situations often arise where clinical appearance and impression from a superficial histopathologic examination are misleading and may direct to a completely erroneous diagnosis. These pitfalls in diagnosis are most significant when they involve various tumors with a malignant potential. In these diseases, a misdiagnosis is likely to have serious medical consequences. It is important to be aware of these specific histological mimickers, because only then may the dermatopathologist be able to detect the subtle changes that lead to a correct diagnosis. Clinical–pathological correlation is also essential. Entities that are prone to misdiagnosis can generally be divided into three categories: skin malignancies that resemble reactive conditions or benign neoplasms; benign conditions that masquerade as malignancies; and tumors that may be mi...
皮肤病理学的陷阱:当事情不是他们看起来的那样
通过整合皮肤病变的临床特征及其组织学发现,皮肤病理学家通常能够正确诊断大多数皮肤疾病。然而,通常情况下,临床表现和印象从表面的组织病理学检查是误导,并可能导致一个完全错误的诊断。当涉及到各种有恶性潜能的肿瘤时,这些诊断缺陷是最显著的。在这些疾病中,误诊可能会造成严重的医疗后果。重要的是要意识到这些特定的组织学模拟物,因为只有这样,皮肤病理学家才能检测到导致正确诊断的细微变化。临床病理相关性也是必不可少的。容易误诊的实体通常可分为三类:类似反应性状况的皮肤恶性肿瘤或良性肿瘤;伪装成恶性肿瘤的良性状况;肿瘤可能是…
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