A pervasive review on biomarker in cervical intraepithelial lesions and carcinoma

Alireza Heidari, Victoria Peterson
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引用次数: 24

Abstract

Basically, medical diagnosis problems are the most effective component of treatment policies. Recently, significant advances have been formed in medical diagnosis fields using data mining techniques. Data mining or Knowledge Discovery is searching large databases to discover patterns and evaluate the probability of next occurrences. In this research, Bayesian Classifier is used as a Non-linear datamining tool to determine the seriousness of breast cancer. The recorded observations of the Fine Needle Aspiration (FNA) tests that are obtained at the University of Wisconsin are considered as experimental data set in this research. The Tabu search algorithm for structural learning of Bayesian classifier and Genie simulator for parametric learning of Bayesian classifier were used. Finally, the obtained results by the proposed model were compared with actual results. The comparison process indicates that seriousness of the disease in 86.18% of cases are guessed very close to the actual values by proposed model. 
宫颈上皮内病变和癌的生物标志物研究综述
基本上,医疗诊断问题是治疗政策中最有效的组成部分。近年来,数据挖掘技术在医学诊断领域取得了重大进展。数据挖掘或知识发现是搜索大型数据库以发现模式并评估下一次发生的概率。在本研究中,贝叶斯分类器作为一种非线性数据挖掘工具来确定乳腺癌的严重程度。在威斯康星大学获得的细针抽吸(FNA)测试的记录观察结果被认为是本研究的实验数据集。使用禁忌搜索算法进行贝叶斯分类器的结构学习,使用Genie模拟器进行贝叶斯分类器的参数学习。最后,将所提模型得到的结果与实际结果进行了比较。比较结果表明,86.18%的病例的病情严重程度与模型的实际值非常接近。
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