The protective effect of gallic acid on tartrazine-induced renotoxicity: Redox potential and morphological study

Abstract

Tartrazine (Tz) is a commonly used artificial food dye which adversely impacts the health status. A broad spectrum of literatures indicates that gallic acid (GA) exert antioxidant and cytoprotective effects. Therefore, this study aimed to estimate the effect of four fold permitted dose of Tz as well as protective effects of GA on Tz-induced renotoxicity in adult male Wistar rats. Tz was administered daily at a dose of 30 mg/kg body weight alone orally, in combination with GA