Mechanical ventilation during extracorporeal membrane oxygenation

Abstract

Extracorporeal membrane oxygenation is a technique for providing temporary extracorporeal respiratory circulation support in patients with respiratory failure who are difficult to treat with conventional therapy (mechanical ventilation). During extracorporeal membrane oxygenation, blood exits from the patient′s venous system, and then enters the artificial membrane lung for oxygenation and carbon dioxide removal, and finally returned to the patient.In order to avoid the loss of normal lung function, mechanical ventilation is still necessary in the process of extracorporeal membrane oxygenation, but there is no clear guidance on how to set mechanical ventilation parameters during extracorporeal membrane oxygenation.Therefore, this article will briefly describe the pathophysiological mechanisms of gas exchange during extracorporeal membrane oxygenation, and summarize the mechanical ventilation strategies in the extracorporeal membrane oxygenation process with available evidence and literature. Key words: Respiration, artificial; Tidal volume; Positive-Pressure Respiration; Extracorporeal membrane oxygenation; Driving pressure