Evaluation of the Relationship Between Vitamin D Levels and Anxiety and Depression in Patients with Chronic Pain

IF 0.2 Q4 RHEUMATOLOGY

Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis Pub Date : 2021-08-01 DOI:10.4274/tod.galenos.2020.47855

Senem Şaş, Fatmanur Aybala Koçak, B. Büyükturan, Ö. Büyükturan

{"title":"Evaluation of the Relationship Between Vitamin D Levels and Anxiety and Depression in Patients with Chronic Pain","authors":"Senem Şaş, Fatmanur Aybala Koçak, B. Büyükturan, Ö. Büyükturan","doi":"10.4274/tod.galenos.2020.47855","DOIUrl":null,"url":null,"abstract":"Objective: This study aimed to determine the relationship between vitamin D levels and anxiety and depression in patients with chronic pain. Materials and Methods: A total of 160 patients, including 125 female and 35 male patients, who were >18 years old and capable of answering study questions were included in this study. Age, gender, height, weight, duration of disease, diagnosis and comorbid status of the patients were recorded. Body mass index (BMI) (kg/m 2 ) was calculated for each patient. Pain was evaluated using the visual analogue scale (VAS), which ranges from 0 to 10. Hospital anxiety and depression scale (HADS) scores were recorded. The patients were divided into two groups (group 1 vitamin D: 0-19, group 2 vitamin D: 20-60 ng/mL) according to vitamin D levels. Also vitamin D levels were noted. Results: The mean age of the patients included in this study was 58.72±8.21 years. Vitamin D deficiency was found in 42.8% of the patients, of which 80.7% were female patients.In patients with chronic pain, there was no correlation between vitamin D levels and age (r=0.185, p=0.026); BMI (r=0.084, p=0.316); disease duration (r=0.067, p=0.420); VAS (r=0.038, p=0.648); HADS scores for anxiety (r=0.020, p=0.808) and HADS scores for depression (r=0.048, p=0.569). No relationship was noted between BMI and vitamin D levels (r =-0.117, p=0.165) in patients with chronic pain; however, a positive correlation was noted between BMI and VAS (r=0.305, p=0.000) and HADS scores for anxiety (r=0.185, p=0.001) and HADS scores for depression (r=0.0240, p=0.002). Abstract Conclusion: In the present study, we found no relationship between vitamin D levels and anxiety and depression in patients with chronic pain. However, we found a correlation between obesity and pain severity. Also we report that obesity is associated with anxiety and depression. Implementing lifestyle changes, such as weight loss and reduction of vitamin D deficiency, can improve anxiety and depression in patients with chronic pain.","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/tod.galenos.2020.47855","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study aimed to determine the relationship between vitamin D levels and anxiety and depression in patients with chronic pain. Materials and Methods: A total of 160 patients, including 125 female and 35 male patients, who were >18 years old and capable of answering study questions were included in this study. Age, gender, height, weight, duration of disease, diagnosis and comorbid status of the patients were recorded. Body mass index (BMI) (kg/m 2 ) was calculated for each patient. Pain was evaluated using the visual analogue scale (VAS), which ranges from 0 to 10. Hospital anxiety and depression scale (HADS) scores were recorded. The patients were divided into two groups (group 1 vitamin D: 0-19, group 2 vitamin D: 20-60 ng/mL) according to vitamin D levels. Also vitamin D levels were noted. Results: The mean age of the patients included in this study was 58.72±8.21 years. Vitamin D deficiency was found in 42.8% of the patients, of which 80.7% were female patients.In patients with chronic pain, there was no correlation between vitamin D levels and age (r=0.185, p=0.026); BMI (r=0.084, p=0.316); disease duration (r=0.067, p=0.420); VAS (r=0.038, p=0.648); HADS scores for anxiety (r=0.020, p=0.808) and HADS scores for depression (r=0.048, p=0.569). No relationship was noted between BMI and vitamin D levels (r =-0.117, p=0.165) in patients with chronic pain; however, a positive correlation was noted between BMI and VAS (r=0.305, p=0.000) and HADS scores for anxiety (r=0.185, p=0.001) and HADS scores for depression (r=0.0240, p=0.002). Abstract Conclusion: In the present study, we found no relationship between vitamin D levels and anxiety and depression in patients with chronic pain. However, we found a correlation between obesity and pain severity. Also we report that obesity is associated with anxiety and depression. Implementing lifestyle changes, such as weight loss and reduction of vitamin D deficiency, can improve anxiety and depression in patients with chronic pain.

查看原文本刊更多论文

慢性疼痛患者维生素D水平与焦虑、抑郁关系的评价

目的:研究慢性疼痛患者维生素D水平与焦虑、抑郁的关系。材料与方法:本研究共纳入160例患者，其中女性125例，男性35例，年龄>18岁，能够回答研究问题。记录患者的年龄、性别、身高、体重、病程、诊断及合并症情况。计算每位患者的身体质量指数(BMI) (kg/ m2)。采用视觉模拟评分(VAS)对疼痛进行评分，评分范围从0到10。记录医院焦虑抑郁量表(HADS)评分。根据维生素D水平将患者分为两组(1组维生素D: 0 ~ 19 ng/mL, 2组维生素D: 20 ~ 60 ng/mL)。同时也记录了维生素D水平。结果:本组患者平均年龄58.72±8.21岁。42.8%的患者存在维生素D缺乏症，其中80.7%为女性。在慢性疼痛患者中，维生素D水平与年龄无相关性(r=0.185, p=0.026);BMI (r=0.084, p=0.316);病程(r=0.067, p=0.420);VAS (r=0.038, p=0.648);焦虑总分(r=0.020, p=0.808)和抑郁总分(r=0.048, p=0.569)。慢性疼痛患者的BMI与维生素D水平无相关性(r =-0.117, p=0.165);然而，BMI和VAS评分(r=0.305, p=0.000)与HADS焦虑评分(r=0.185, p=0.001)和HADS抑郁评分(r=0.0240, p=0.002)呈正相关。结论:在本研究中，我们发现维生素D水平与慢性疼痛患者的焦虑和抑郁之间没有关系。然而，我们发现肥胖和疼痛严重程度之间存在相关性。我们还报道肥胖与焦虑和抑郁有关。改变生活方式，如减肥和减少维生素D缺乏症，可以改善慢性疼痛患者的焦虑和抑郁。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis RHEUMATOLOGY-

CiteScore

0.30

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Turkish Journal Of Osteoporosis is the regular publishing organ of the Turkish Osteoporosis Society. This periodical journal covers osteoporosis and metabolic bone diseases subjects. It is a periodic international journal, published in Turkish and English languages and is independent, being based on peer-review principles. The journal is published 3 times per year (April, August and December). The aim of the journal “Turkish Journal Of Osteoporosis” is to continuously publish original research papers of the highest scientific and clinical values specifically on osteoporosis, on an international level. Additionally, reviews on basic developments in education, editorial short notes, case reports, original views, letters from the fields of physical medicine, rheumatology, rehabilitation, gynaecology containing experiences and comments as well as social subjects are published. ‘Thing that must be known’ subjects for general practitioners giving first line medical service who are interested in osteoporosis and metabolic bone diseases, specialists in internal medicine, gynecology, rheumatology and physiotherapy will be determined It will then be possible to make the necessary adjustments to the journal “Turkish Journal Of Osteoporosis” according to their needs.