THE COMBINATION OF SALBUTAMOL NEBULIZER AND PROCATEROL ORAL TO THE INDONESIAN CHILDREN WITH PNEUMONIA

Abstract

This study aimed to examine the effectiveness of combining salbutamol nebulizer and procaterol oral compared to only procaterol oral on the respiratory status including temperature (fever), spasm, cough, retraction and length of stay (LOS), among young children with pneumonia. This prospective cohort study included 48 consecutive sampling subjects with pneumonia in Indonesia. The subjects were classified based on the type of therapy they received: intervention group used the combination of salbutamol nebulizer and procaterol oral therapy (n = 24) and the control group used procaterol oral only (n = 24). The study of the two groups showed that the combination salbutamol nebulizer and procaterol oral was more effective than the administration of procaterol oral only with the rate of clinical change. The significant effectiveness of nebulizer salbutamol and oral procaterol to reducing respiratory status (p=0.006) and temperature (fever) (p=0.000) compared to the only procaterol oral. However, there was no significant effectiveness of nebulizer salbutamol and oral procaterol in reducing spasm (p=0.348), cough (p=0.964), retraction (p=0.666) and length of stay (LOS) (p=0.192) compared to the only procaterol oral among the Indonesian children with pneumonia.