Georgia Papadogeorgou, Fiammetta Menchetti, Christine Choirat, Jason H Wasfy, Corwin M Zigler, Fabrizia Mealli
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引用次数: 0
Abstract
Researchers are often faced with evaluating the effect of a policy or program that was simultaneously initiated across an entire population of units at a single point in time, and its effects over the targeted population can manifest at any time period afterwards. In the presence of data measured over time, Bayesian time series models have been used to impute what would have happened after the policy was initiated, had the policy not taken place, in order to estimate causal effects. However, the considerations regarding the definition of the target estimands, the underlying assumptions, the plausibility of such assumptions, and the choice of an appropriate model have not been thoroughly investigated. In this paper, we establish useful estimands for the evaluation of large-scale policies. We discuss that imputation of missing potential outcomes relies on an assumption which, even though untestable, can be partially evaluated using observed data. We illustrate an approach to evaluate this key causal assumption and facilitate model elicitation based on data from the time interval before policy initiation and using classic statistical techniques. As an illustration, we study the Hospital Readmissions Reduction Program (HRRP), a US federal intervention aiming to improve health outcomes for patients with pneumonia, acute myocardial infraction, or congestive failure admitted to a hospital. We evaluate the effect of the HRRP on population mortality among the elderly across the US and in four geographic subregions, and at different time windows. We find that the HRRP increased mortality from pneumonia and acute myocardial infraction across at least one geographical region and time horizon, and is likely to have had a detrimental effect on public health.
期刊介绍:
The journal reflects the multidisciplinary nature of the field of health services and outcomes research. It addresses the needs of multiple, interlocking communities, including methodologists in statistics, econometrics, social and behavioral sciences; designers and analysts of health policy and health services research projects; and health care providers and policy makers who need to properly understand and evaluate the results of published research. The journal strives to enhance the level of methodologic rigor in health services and outcomes research and contributes to the development of methodologic standards in the field. In pursuing its main objective, the journal also provides a meeting ground for researchers from a number of traditional disciplines and fosters the development of new quantitative, qualitative, and mixed methods by statisticians, econometricians, health services researchers, and methodologists in other fields. Health Services and Outcomes Research Methodology publishes: Research papers on quantitative, qualitative, and mixed methods; Case Studies describing applications of quantitative and qualitative methodology in health services and outcomes research; Review Articles synthesizing and popularizing methodologic developments; Tutorials; Articles on computational issues and software reviews; Book reviews; and Notices. Special issues will be devoted to papers presented at important workshops and conferences.