Cytisine parameters measured in the 1.5 Tesla magnetic field

Zuzanna Bober, Sabina Galiniak, Dawid Leksa, Klaudia Dynarowicz, D. Aebisher, Elżbieta Ostańska, Anna Czmil, P. Bar, D. Bartusik-Aebisher, P. Tutka
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Abstract

Introduction. Cytisine, Cytisinum (C11H14N2O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substance.
在1.5特斯拉磁场中测量的胞嘧啶参数
介绍。Cytisine, Cytisinum (C11H14N2O)是一种有机化合物。胱氨酸是一种杂三环化合物,是Laburnum种子中的有毒成分,在豆科(豆类、豌豆或豆类)的许多成员中都有发现。的目标。本研究的目的是测量水在1.5特斯拉磁场中对药物形态的影响。材料和方法。为此,进行了磁共振成像测试,以检查纯胱氨酸,地莫昔片和他贝昔胶囊的溶解度。结果。从药理学的角度来看,Desmoxan片剂和Tabex胶囊应该对人体产生相同的作用,这是由于活性物质的含量相同,在本例中为胱氨酸(1.5 mg)。结论。所得结果的差异可能与含有药物的附加赋形剂有关,但据信它们不应对活性物质的作用产生负面影响。
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