Blood and Bone Marrow Transplantation for Acute Myeloid Leukemia

Luis M. Villela , Javier Bolaños-Meade
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引用次数: 3

Abstract

Bone marrow transplantation is the treatment of choice for some patients with acute myeloid leukemia and myelodysplastic syndrome (MDS). Patients with high-risk disease, such as those with MDS, in second (or subsequent) complete remission or those with poor-risk cytogenetics will benefit the most from this approach. With current transplantation techniques, outcomes have improved over recent years. Although relapse and graft-versus-host disease still are important problems faced by these patients, novel approaches have been developed to decrease the risk of complications, with excellent results.

血液和骨髓移植治疗急性髓性白血病
骨髓移植是一些急性髓性白血病和骨髓增生异常综合征(MDS)患者的治疗选择。高风险疾病患者,如MDS患者,第二次(或后续)完全缓解或低风险细胞遗传学患者将从该方法中获益最多。随着目前移植技术的发展,近年来移植的效果有所改善。尽管复发和移植物抗宿主病仍然是这些患者面临的重要问题,但已经开发出新的方法来降低并发症的风险,并取得了良好的效果。
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