Acute toxicity of nitrite in fat snook (Centropomus parallelus)

IF 0.9 4区生物学 Q3 MARINE & FRESHWATER BIOLOGY

Marine and Freshwater Behaviour and Physiology Pub Date : 2018-01-02 DOI:10.1080/10236244.2018.1447850

Andressa de Souza Lima Rodrigues, K. G. Gnocchi, Frederico Augusto Cariello Delunardo, L. Medeiros, J. Merçon, L. C. Gomes

引用次数: 0

Abstract

Abstract Oxidative stress and hypoxia responses in Centropomus parallelus exposed to three different concentrations of nitrite (0, 0.5, and 10 mg L−1) were evaluated. To determinate toxicity, we used enzymatic analyses and quantifications of oxygen consumption and opercular beats under conditions of normoxia and hypoxia. There was no significant difference in GST, CAT, or GPx enzymes in the liver or in GPx in the gills. Levels of GST were altered at a concentration of 10 mg L−1 in experiment I. Experiment II displayed alterations for GST and CAT in the liver at the same concentration, indicating that exposure to nitrite does not generate differentiated activation in the body’s defense system by the production of oxidative stress enzymes. When nitrite was associated with hypoxia, there was a significant increase in both enzymatic activity and opercular beating under hypoxia in the group exposed to 10 mg L−1 nitrite compared to the control.

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亚硝酸酯对大鼠的急性毒性研究

摘要研究了平行centrropomus parallelus暴露于3种不同浓度亚硝酸盐(0、0.5和10 mg L−1)下的氧化应激和缺氧反应。为了确定毒性，我们在常氧和缺氧条件下使用酶分析和定量耗氧量和眼搏动。肝脏中GST、CAT、GPx酶和鳃中GPx酶无显著差异。实验1中，GST水平在浓度为10 mg L−1时发生了变化。实验2显示，在相同浓度下，肝脏中GST和CAT的变化表明，接触亚硝酸盐不会通过产生氧化应激酶来产生机体防御系统的分化激活。当亚硝酸盐与缺氧相关时，与对照组相比，暴露于10 mg L−1亚硝酸盐的组在缺氧条件下酶活性和眼球跳动均显著增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Marine and Freshwater Behaviour and Physiology 生物-海洋与淡水生物学

CiteScore

2.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Marine and Freshwater Behaviour and Physiology is devoted to the publication of papers covering field and laboratory research into all aspects of the behaviour and physiology of all marine and freshwater animals within the contexts of ecology, evolution and conservation. As the living resources of the world’s oceans, rivers and lakes are attracting increasing attention as food sources for humans and for their role in global ecology, the journal will also publish the results of research in the areas of fisheries biology and technology where the behaviour and physiology described have clear links to the contexts mentioned above. The journal will accept for publication Research Articles, Reviews, Rapid Communications and Technical Notes (see Instructions for authors for details). In addition, Editorials, Opinions and Book Reviews (invited and suggested) will also occasionally be published. Suggestions to the Editor-In-Chief for Special Issues are encouraged and will be considered on an ad hoc basis. With the goal of supporting early career researchers, the journal particularly invites submissions from graduate students and post-doctoral researchers. In addition to recognising the time constraints and logistical limitations their research often faces, and their particular need for a prompt review process, accepted articles by such researchers will be given prominence within the journal (see Instructions for authors for details).