Characterization and Antioxidant Activity of Platinum Nanoparticles Synthesized by Using Cetraria Islandica Extract

Abstract

Platinum nanoparticles (Pt NPs) have structural properties that differ from their bulk forms, such as physical and chemical properties. The cost and toxicity problems caused by the synthesis of Pt NPs, which are widely used in biomedical fields, by laser ablation, aerosol, sol-gel, co-precipitation, and chemical reduction techniques are eliminated by the biological synthesis method. In this study, the biosynthesis of Cetraria islandica extract based Pt NPs was performed in PBS buffer (pH 7.4) and their antioxant activity was evaluated. With FE-SEM images, it was observed that Pt NPs had a spherical structure, aggregation tendency and an average diameter of 62 nm. The presence of Pt in the structure of NPs was observed by EDX analysis. With the peaks obtained by FT-IR analysis, the presence of C=O (amide), C-O (aliphatic ether), CO-O-CO (anhydride), C=C (alkene) and Pt were recorded and biomolecular groups that play a role in the synthesis were revealed. It was determined that Pt NPs synthesized via C. islandica extract had antioxidant activity (92.4 ug/ml, R2=0.8727). As a conclusion, biosynthesis of Pt NPs with C. islandica extract was carried out as an alternative to physical and chemical methods, and its antioxidant activity was revealed. It is thought that the obtained data can be used in biomedical fields.