Lyme Arthritis: A Primer for Primary Care

Ganesh Arun, Farhan Ali, S. Srinivas, J. Nistico, Pranav Nair
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Abstract

Lyme disease is caused by a bacteria belonging to the Borreliaceae family. Wooded forests and terrains are affected, including those in the Northeastern United States. Teenage ticks are most commonly discovered on humans as those ticks need to satisfy their nutritional requirements for growth. They bite warm, moist areas of the body and take 24 to 48 hours to transmit the Borrelia Burgdorferi infection. Lyme disease manifests as a multisystem disorder in humans, and is known for its dermatological, neurological and rheumatological findings. For the primary care provider, Lyme disease should be on the differential in multisystem diseases. Our case is a 63 year old gentleman who presented with unilateral knee pain for the last 3 months. He initially visited the outpatient orthopedic outpatient office for this arthritic pain. Before moving forward with knee replacement he was eventually tested for Lyme Serology IgG and IgM tests. His positive results warranted Lyme Western Blot testing which confirmed the suspicion of lyme arthritis secondary to Borrelia Burgdorferi. He was treated with a 14 day course of doxycycline, which resulted in significant improvement of knee pain and return to baseline functionality without surgical intervention. The purpose of this report is to stress the importance of beginning doxycycline as soon as possible to avoid progression into other organ systems such as worsening rheumatologic arthritis, central nervous system neuropathies, peripheral nervous system palsies, or cardiac atrioventricular blocks. The optimal treatment is obtained with thorough history taking and physical examination.
莱姆病:初级保健入门
莱姆病是由Borreliaceae家族的一种细菌引起的。森林和地形受到影响,包括美国东北部的森林和地形。青少年蜱虫最常在人类身上发现,因为这些蜱虫需要满足它们生长的营养需求。它们叮咬身体温暖潮湿的部位,需要24到48小时才能传播伯氏疏螺旋体感染。莱姆病在人类中表现为一种多系统疾病,以其皮肤、神经和风湿病表现而闻名。对于初级保健提供者,莱姆病应在多系统疾病的区别。我们的病例是一位63岁的绅士,他在过去的3个月里表现出单侧膝盖疼痛。他最初因关节炎疼痛到骨科门诊就诊。在进行膝关节置换术之前,他最终进行了莱姆病血清IgG和IgM测试。他的阳性结果证实了莱姆病免疫印迹检测证实了继发于伯氏疏螺旋体的莱姆病关节炎的怀疑。患者接受了14天的强力霉素治疗,在没有手术干预的情况下,膝关节疼痛得到了显著改善,功能恢复到基线水平。本报告的目的是强调尽早开始使用强力霉素的重要性,以避免进展到其他器官系统,如恶化的风湿性关节炎、中枢神经系统神经病、周围神经系统麻痹或心脏房室传导阻滞。最好的治疗方法是通过详细的病史记录和体格检查。
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