Colposcopic Evaluation of Clinically Unhealthy Cervix

K. Akter, S. Nasreen, D. Islam, Sakhawat Hossain
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Abstract

Cervical cancer is the commonest malignancy found amongst Bangladeshi women and the third most common cancer in the world. New cases of invasive cervical cancer are diagnosed over 5,00,000 annually worldwide. For Cervical Intra-Epithelial Neoplasia (CIN) and for invasive cancer of the uterine cervix, Papanicolaou’s (Pap) smear is the primary screening tool. The Pap smear accuracy, which was recently assumed found to be 80% to 95% for detecting CIN and early invasive cancer, was questioned. Colposcopy and directed biopsy are needed to clarify the clinically unhealthy cervix in women. This study was conducted to evaluate the role of colposcopy in identifying. The aim of the study was to assess the role of colposcopy of the unhealthy cervix to localize the lesions and to obtain biopsies from the selected areas. This prospective observational study conducted from January 2016 to December 2016 in the Department of Obstetrics and Gynaecology, Sikder Medical College, Dhaka including 104 patients who were aged between 25-65 years with clinically unhealthy cervix, were exposed to a colposcopic evaluation. All the patients underwent colposcopic-directed biopsies. The biopsies were taken from the act white areas and the iodine negative areas. Among 104 patients, 49 (47.1%) were in the age group of 25-34 years. In the parity, 97 (93.3%) 0-4 child, 61 (58.7%) were married before 18 years of age. 17 (16.35%) had normal colposcopic findings. The colposcopic evaluation and the guided biopsy were successful in detecting abnormalities in 26 out of 31 cases. The incidence of CIN 1 and CIN2, 3 were found colposcopically and histologically 33.65%, 24.04%, and 11.54%, respectively. In the present study, the sensitivity of colposcopy was 83.33%. Both the neoplastic and the non-neo-plastic ones, colposcopy was found to be useful in understanding the morphology of the cervical lesions and this would very helpful in planning their management in the future.
临床不健康子宫颈的阴道镜评价
宫颈癌是孟加拉国妇女中最常见的恶性肿瘤,也是世界上第三大常见癌症。全世界每年诊断出的侵袭性宫颈癌新病例超过50万例。对于宫颈上皮内瘤变(CIN)和宫颈浸润性癌,巴氏涂片是主要的筛查工具。巴氏涂片检测CIN和早期浸润性癌症的准确性最近被认为为80%至95%,但受到质疑。需要阴道镜检查和指导活检来澄清临床不健康的妇女宫颈。本研究旨在评估阴道镜检查在鉴别。本研究的目的是评估阴道镜检查不健康子宫颈的作用,以确定病变的位置,并从选定的区域进行活检。本前瞻性观察性研究于2016年1月至2016年12月在达卡Sikder医学院妇产科进行,包括104名年龄在25-65岁之间临床宫颈不健康的患者,接受阴道镜评估。所有患者均行阴道镜下活检。活检分别取自白色区和碘阴性区。104例患者中有49例(47.1%)年龄在25-34岁之间。胎次中,0-4岁儿童97例(93.3%),18岁前结婚61例(58.7%)。17例(16.35%)阴道镜检查结果正常。31例患者中26例经阴道镜检查及穿刺活检成功检出异常。阴道镜检查CIN 1、CIN2、CIN 3的发生率分别为33.65%、24.04%、11.54%。本研究中,阴道镜检查的敏感性为83.33%。无论是肿瘤性的还是非新成形性的,阴道镜检查都有助于了解宫颈病变的形态,这将对今后的治疗计划非常有帮助。
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