EFFECTS OF LONG-TERM USE OF ETONOGESTREL CONTRACEPTIVE IMPLANT: LITERATURE REVIEW

Siang Br Tarigan
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Abstract

Implantable contraceptives are a long-term birth control option for women. However, contraceptive implants are not suitable for everyone. One of the contraceptive implants that is often used is etonogestrel. Etonogestrel is a progestin, or synthetic progestogen, and is therefore an agonist of the progesterone receptor, the biological target of progestogens such as progesterone. It works by stopping ovulation, thickening the mucus around the cervical opening, and changing the lining of the uterus. It has very weak androgenic and glucocorticoid activity and no other important hormonal activity. The purpose of this study was to determine the side effects of long-term use of the etonogestrel implant contraceptive through a literature study. The three databases used are Pubmed, ScienceDirect, and Scopus in this study. The literature search was carried out after the PICO was determined and used the keywords “Effect”, “Etonogestrel Contraceptive Implant”, “Long Term”. Based on the analysis of the 11 articles obtained in this study, it can be concluded that the Etonogestrel Implant Contraceptive is a safe and effective contraceptive method for use in women of childbearing age. Even so, etonogestrel has side effects such as menstrual irregularities, breast tenderness, mood swings, acne, headaches, vaginitis
长期使用炔诺孕酮避孕植入物的影响:文献综述
对于女性来说,植入式避孕药是一种长期的避孕选择。然而,避孕植入物并不适合所有人。一种常用的避孕植入物是炔诺孕酮。依托孕酮是一种黄体酮或合成黄体酮,因此是黄体酮受体的激动剂,黄体酮是黄体酮等黄体酮的生物学靶点。它的工作原理是停止排卵,增厚宫颈口周围的粘液,改变子宫内膜。它具有非常弱的雄激素和糖皮质激素活性,没有其他重要的激素活性。本研究的目的是通过文献研究来确定长期使用炔诺孕酮植入避孕药的副作用。本研究使用的三个数据库分别是Pubmed、ScienceDirect和Scopus。确定PICO后进行文献检索,检索关键词为“Effect”、“Etonogestrel避孕植入物”、“Long Term”。通过对本研究获得的11篇文献的分析,可以得出依诺孕酮植入避孕药是一种安全有效的育龄妇女避孕方法。即便如此,炔诺孕酮也有副作用,比如月经不规律、乳房胀痛、情绪波动、痤疮、头痛、阴道炎
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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