The Internal COVID-19 Database Registry: A Rural, Community Hospital’s Experience with the Pandemic

M. Assaad, A. Karki
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Abstract

The COVID-19 pandemic has brought to light several long-term complications that may be challenging for clinicians to manage. Therefore, it is imperative for physicians to be able to identify patients at risk for infection and to understand the deleterious physiologic and clinical effects the virus can have on long-term lung function. The authors utilized the internal COVID-19 database registry at a rural, community hospital to identify the presence of pulmonary-specific conditions that may have predisposed the patient population to infection. Data were collected from 1,329 patients admitted to the hospital between March 2020 and November 2021. Data regarding patient demographics, vaccination status, baseline pulmonary conditions, and pulmonary function tests were collected. All statistical analysis was carried out in R statistical programming language (R Core Team, 2021). The pulmonary condition that had the highest mortality rate (42.86%) was obesity hypoventilation syndrome; however, the total number of patients with this diagnosis was only 7. With regards to change in pulmonary function parameters following admission, the only variable that was found to be statistically significant was a decrease in DLCO (diffusing capacity) for patients who survived. Interestingly, there was no statistically significant difference in mortality among vaccinated patients. Although some confounding variables may exist, the registry database may prove clinically useful to help guide physicians in establishing disease patterns and better managing long-term complications from COVID-19. Additional variables of interest to measure may include new imaging findings of pulmonary fibrosis, development of pulmonary hypertension, and new oxygen requirements.
内部COVID-19数据库注册:农村社区医院应对大流行的经验
COVID-19大流行暴露了临床医生可能难以应对的一些长期并发症。因此,医生必须能够识别有感染风险的患者,并了解病毒对长期肺功能可能产生的有害生理和临床影响。作者利用一家农村社区医院的内部COVID-19数据库登记处来确定是否存在可能使患者易感染的肺部特异性疾病。数据收集自2020年3月至2021年11月期间入院的1329名患者。收集有关患者人口统计学、疫苗接种状况、基线肺部状况和肺功能检查的数据。所有统计分析均使用R统计编程语言进行(R Core Team, 2021)。死亡率最高的肺部疾病是肥胖低通气综合征(42.86%);然而,这种诊断的患者总数仅为7例。关于入院后肺功能参数的变化,发现唯一具有统计学意义的变量是存活患者的DLCO(弥散能力)下降。有趣的是,接种疫苗的患者死亡率没有统计学上的显著差异。尽管可能存在一些混杂变量,但注册数据库可能在临床上有用,有助于指导医生建立疾病模式并更好地管理COVID-19的长期并发症。需要测量的其他变量可能包括肺纤维化的新影像学表现、肺动脉高压的发展和新的氧气需要量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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