Transcutaneous biochemical substance monitoring based on biosensors-blood glucose and lactate

M. Kikuchi, S. Kayashima, N. Ito, T. Arai
{"title":"Transcutaneous biochemical substance monitoring based on biosensors-blood glucose and lactate","authors":"M. Kikuchi, S. Kayashima, N. Ito, T. Arai","doi":"10.1109/IEMBS.1996.656861","DOIUrl":null,"url":null,"abstract":"New transcutaneous monitoring methods for biochemical substances such as blood glucose and lactate have been developed by using a suction effusion fluid (SEF) collecting technique with an ion-sensitive field-effect transistor for blood glucose, and with a micro-planar amperometric biosensor for lactate respectively. Firstly, blood glucose change during the 75-g oral glucose tolerance test (OGTT) was monitored by suction effusion fluid (SEF) sampling in 5 patients with type II diabetes. Secondly, the authors have also developed a micro planar biosensor for determining lactate concentration in very small sample. The biosensor utilizes a lactate oxidase immobilized membrane on a micro planar platinum electrode to yield a lactate sensor. Both glucose and lactate concentrations measured with SEF showed good correlation with those obtained directly from whole blood.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1996.656861","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

New transcutaneous monitoring methods for biochemical substances such as blood glucose and lactate have been developed by using a suction effusion fluid (SEF) collecting technique with an ion-sensitive field-effect transistor for blood glucose, and with a micro-planar amperometric biosensor for lactate respectively. Firstly, blood glucose change during the 75-g oral glucose tolerance test (OGTT) was monitored by suction effusion fluid (SEF) sampling in 5 patients with type II diabetes. Secondly, the authors have also developed a micro planar biosensor for determining lactate concentration in very small sample. The biosensor utilizes a lactate oxidase immobilized membrane on a micro planar platinum electrode to yield a lactate sensor. Both glucose and lactate concentrations measured with SEF showed good correlation with those obtained directly from whole blood.
基于生物传感器的经皮生化物质监测-血糖和乳酸
采用离子敏感场效应晶体管的吸力积液采集技术和微平面安培型生物传感器的乳酸监测技术,建立了经皮监测血糖和乳酸等生化物质的新方法。首先,对5例2型糖尿病患者进行75 g口服葡萄糖耐量试验(OGTT)期间的血糖变化,采用吸液(SEF)取样法进行监测。其次,作者还开发了一种微型平面生物传感器,用于测定极小样品中的乳酸浓度。该生物传感器利用在微平面铂电极上的乳酸氧化酶固定化膜来产生乳酸传感器。SEF测量的葡萄糖和乳酸浓度与直接从全血中获得的浓度具有良好的相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信