Respiratory Rehabilitation in Patients with Abdominal Aortic Aneurysm Submitted to OPEN and EVAR Treatment: Predictive Factors of Postoperative Pulmonary Complications and Clinical Implications

A. Marchetti, G. Citoni, C. Foti, A. Ippoliti
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Abstract

Background: In the conventional surgical treatment of aneurysms, the respiratory physiotherapy is one of the cornerstones of patient rehabilitation. The endovascular technique, with less invasiveness, has significantly changed the rehabilitative approach to the operated subject. Objective of the study: to evaluate and compare the effectiveness of the pre and post-operative rehabilitation treatment associated with the conventional OPEN surgery compared to the EVAR procedure and their incidence in preventing postoperative respiratory complications. Design: Longitudinal case control study to compare patients who have open surgery with patients who do not have the laparotomy, as in ENDO technique, to look how frequently the postoperative pneumonia and the risk factor was present in each group to determine the relationship between the risk factor, the type of operation and the pneumonia incidence. Setting Data were collected from patients admitted consecutively at the Tor Vergata Hospital with diagnosis of an abdominal aortic aneurysm. Risk factors, type of intervention, pneumonia incidence in postoperative period was evaluted at 30 days. Population: Three hundred and twenty patient were enrolled. Materials and methods: From 2005 to 2016, 320 patients suffering from an abdominal aortic aneurysm were treated consecutively. One hundred eighty one patients were treated using the open technique (group A) and 139 using the EVAR technique (group B). All patients in OPEN group were submitted to respiratory rehabilitation protocol. Risk factors, type of intervention, anesthesia and results of treatment with complications, observed mortality, mean hospital stay were studied. Pre and postoperative respiratory rehabilitation treatment protocol was performed in all of the patients. The data were analyzed with descriptive statistics and inferential statistics using SPSS 18.0 for Windows. Results: From 2005-2010, the postoperative stay (days) was significant shorter for EVAR compared to open (6.47 vs. 10.48; P 0.001). From 2011-2016, the postoperative stay (days) was significant shorter EVAR compared open (4.07 vs. 11.41; P 0.001). The patients treated from 2011 to 2016 for both OPEN and EVAR groups presented an average age 3 years lower compared to the patients treated in the period from 2005-2011 (75.5 to 72.8 for EVAR and from 71,2 to 68,2). The patients treated from 2011 to 2016 for EVAR group presented an average reduction in post-operative hospitalization of 2.4 days (-37.09%) compared to 2005-2011 period. There was a significant higher incidence of pneumonia in the open group (P=0.001). The reduction of the incidence of pneumonia in group A and B during the two different periods from 2005 to 2010 and from 2011 to 2016 was observed. There wasn’t a significant difference in the incidence of pneumonia in patients treated from 2005 to 2010 (P-value=0.1). In patients treated from 2011 to2016 there was a significant increasing the incidence of pneumonia in OPEN group (P=0.001). Conclusion: Rehabilitation physiotherapy plays a fundamental role in the prevention of postoperative complications of patients undergoing OPEN treatment. Despite of the excellent results obteined in patients undergoing OPEN treatment, the lower rate of complications in EVAR group showed better results of this treatment.
腹主动脉瘤经OPEN和EVAR治疗患者的呼吸康复:术后肺部并发症的预测因素及临床意义
背景:在传统的动脉瘤手术治疗中,呼吸物理治疗是患者康复的基石之一。血管内技术侵入性小,显著改变了手术患者的康复方式。本研究目的:评价和比较常规OPEN手术与EVAR手术术前、术后康复治疗的有效性及其在预防术后呼吸并发症方面的发生率。设计:纵向病例对照研究,比较开腹手术患者和未开腹手术患者,如在ENDO技术中,观察每组术后肺炎和危险因素的出现频率,以确定危险因素、手术类型和肺炎发病率之间的关系。数据收集自Tor Vergata医院诊断为腹主动脉瘤的连续住院患者。术后30天评估危险因素、干预方式、肺炎发生率。人群:320例患者入组。材料与方法:2005 - 2016年,对320例腹主动脉瘤患者进行连续治疗。采用开放式技术181例(A组),采用EVAR技术139例(B组)。open组均采用呼吸康复方案。研究危险因素、干预方式、麻醉及并发症治疗结果、观察死亡率、平均住院时间。所有患者均采用术前及术后呼吸康复治疗方案。采用SPSS 18.0 for Windows软件对数据进行描述性统计和推理统计。结果:2005-2010年,EVAR的术后停留时间明显短于开腹手术(6.47 vs. 10.48;P 0.001)。2011-2016年,术后EVAR停留时间(天)明显短于对照组(4.07 vs 11.41;P 0.001)。与2005-2011年治疗的患者相比,2011 - 2016年OPEN组和EVAR组患者的平均年龄降低了3岁(EVAR组为75.5 - 72.8岁,EVAR组为71.2 - 68.2岁)。2011 - 2016年EVAR组患者术后住院时间较2005-2011年平均减少2.4天(-37.09%)。开放组肺炎的发生率明显高于开放组(P=0.001)。观察A组和B组在2005 - 2010年和2011 - 2016年两个不同时期肺炎发病率的下降情况。2005年与2010年两组患者肺炎发生率比较,差异无统计学意义(p值=0.1)。在2011 - 2016年治疗的患者中,OPEN组肺炎的发病率显著增加(P=0.001)。结论:康复物理治疗对预防OPEN术后并发症起着重要作用。尽管接受OPEN治疗的患者获得了良好的效果,但EVAR组并发症发生率较低,表明该治疗效果较好。
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