Brief Communication of Assessment of Clinical Practice Regarding Pharmacological Treatment of Epilepsy: A Survey of Neurologists in Republic of Macedonia

Prilozi Pub Date : 2014-12-01 DOI:10.1515/prilozi-2015-0020

E. Cvetkovska, I. Kuzmanovski, B. Boshkovski

{"title":"Brief Communication of Assessment of Clinical Practice Regarding Pharmacological Treatment of Epilepsy: A Survey of Neurologists in Republic of Macedonia","authors":"E. Cvetkovska, I. Kuzmanovski, B. Boshkovski","doi":"10.1515/prilozi-2015-0020","DOIUrl":null,"url":null,"abstract":"Abstract A questionnaire of 15 items was developed in order to evaluate clinical practice regarding pharmacological treatment of epilepsy among adult neurologists in R. Macedonia. It was mailed to 30 practising neurologists, 24 answered (80%). Half of them administer AED after a first unprovoked seizure considering EEG and MRI, while others usually wait for a second one before introducing treatment. Discontinuation of treatment should be individualized. Carbamazepine and lamotrigine are the most frequently prescribed first-line drugs for partial seizures; second choices include a number of older and new generation AEDs. For generalized tonic-clonic seizures, absences, myoclonic, mixed or undetermined seizures, valproate is by far the most commonly used AED. The survey showed that prescription patterns are in accordance with current evidence about the spectrum of efficacy of individual AEDs in different types of seizures. Yet some results are a cause of concern and continuous education of the neurological community on AED treatment of epilepsy is needed.","PeriodicalId":87202,"journal":{"name":"Prilozi","volume":"816 1","pages":"163 - 166"},"PeriodicalIF":0.0000,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/prilozi-2015-0020","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prilozi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/prilozi-2015-0020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

Abstract

Abstract A questionnaire of 15 items was developed in order to evaluate clinical practice regarding pharmacological treatment of epilepsy among adult neurologists in R. Macedonia. It was mailed to 30 practising neurologists, 24 answered (80%). Half of them administer AED after a first unprovoked seizure considering EEG and MRI, while others usually wait for a second one before introducing treatment. Discontinuation of treatment should be individualized. Carbamazepine and lamotrigine are the most frequently prescribed first-line drugs for partial seizures; second choices include a number of older and new generation AEDs. For generalized tonic-clonic seizures, absences, myoclonic, mixed or undetermined seizures, valproate is by far the most commonly used AED. The survey showed that prescription patterns are in accordance with current evidence about the spectrum of efficacy of individual AEDs in different types of seizures. Yet some results are a cause of concern and continuous education of the neurological community on AED treatment of epilepsy is needed.

查看原文本刊更多论文

关于癫痫药物治疗临床实践评估的简要交流:马其顿共和国神经科医生的调查

摘要为评价马其顿共和国成人神经科医生在癫痫药物治疗方面的临床实践情况，设计了一份包含15个项目的调查问卷。邮寄给30名执业神经科医生，24人回复(80%)。他们中有一半在第一次无端发作后使用AED，考虑脑电图和核磁共振成像，而其他人通常等到第二次发作后再进行治疗。停止治疗应个体化。卡马西平和拉莫三嗪是治疗部分性癫痫最常用的一线药物;第二种选择包括一些旧的和新一代的aed。对于全身性强直阵挛性发作、缺席、肌阵挛性发作、混合性或不确定性发作，丙戊酸是目前最常用的AED。调查显示，处方模式与目前关于不同类型癫痫发作的单个aed的功效谱的证据一致。然而，一些结果引起了关注，需要对神经学界进行AED治疗癫痫的持续教育。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Prilozi

自引率

0.00%

发文量