Informative article. Scaffold in bone tissue engineering

Abstract

Summary Treatment of bone tissue injuries and diseases is still a great challenge for surgeons, but also for researchers who work with materials. Today stem cells are commonly used in bone tissue engineering. However, advances in biocompatible materials design, especially biodegradable porous structure (scaffold) is gaining an important role in the treatment of diseased bone tissue. The basic advantage of these carriers is specifically designed scaffold with defined porosity and pore structure that is favourable for cells settlement. Scaffolds are most commonly used as ceramic brackets because they have excellent characteristics in biodegradation and bioactivity. The process of scaffold production is important because the appropriate technology must ensure control of liquids and reproducibility of scaffold production through standardized process. The aim of this study was to present some of different procedures of scaffold production in bone tissue engineering and point out the advantages and disadvantages of these methods.