Prevalence of type 2 diabetes among persons with disabilities in the South-East Asian region: A systematic review and meta-analysis

Current medical issues Pub Date : 2022-07-01 DOI:10.4103/cmi.cmi_27_22

Rajeswaran Thiagesan, V. Gopichandran, S. Subramaniam, Hilaria Soundari, K. Kosalram

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引用次数: 3

Abstract

Background: Type 2 diabetes is a major public health burden in the South-East Asian region. Persons with disabilities have a higher predilection for developing type 2 diabetes. Objective: The objective of this study was to estimate the prevalence of type 2 diabetes among persons with physical, development, sensory, and psychiatric disabilities in the South-East Asian regional countries. Methods: The Medline database was searched through PubMed using a specifically developed search strategy to identify observational studies that looked at the prevalence of type 2 diabetes among persons with various types of disabilities. Specific inclusion–exclusion criteria were used to shortlist the most relevant studies. The AXIS tool was used to assess the risk of bias in the identified studies. Data were extracted from the final list of studies and meta-analyzed using a random-effects model. Forest plot was used to study the pooled estimate and funnel plot was studied to assess publication bias. Subgroup analysis of prevalence of diabetes among persons with psychiatric and physical disabilities was performed. Results: A total of 771 papers were identified for screening. Of them, 740 were excluded and 31 were included in the full-text review. Finally, 12 studies were included in the meta-analysis. The prevalence of type 2 diabetes among persons with disabilities was 12.8% (95% confidence interval [CI]: 8.8%–16.8%). The studies showed a wide heterogeneity. The funnel plot did not show any publication bias. Subgroup analysis showed that while the prevalence of type 2 diabetes in persons with psychiatric disabilities was 14.0% (95% CI: 9%–18.9%), it was 10.6% (95% CI: 3.6%–17.6%) among persons with other forms of physical disabilities. Conclusion: The prevalence of type 2 diabetes is high among persons with disabilities. There is a need for well-conducted systematic studies in the South-East Asian region on prevalence of type 2 diabetes among persons with disabilities.

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东南亚地区残疾人2型糖尿病患病率:一项系统综述和荟萃分析

背景:2型糖尿病是东南亚地区一个主要的公共卫生负担。残疾人更容易患2型糖尿病。目的:本研究的目的是估计东南亚地区国家身体、发育、感觉和精神残疾人群中2型糖尿病的患病率。方法:通过PubMed检索Medline数据库，使用专门开发的搜索策略来识别观察性研究，这些研究观察了不同类型残疾人中2型糖尿病的患病率。采用特定的纳入-排除标准来筛选最相关的研究。使用AXIS工具评估已确定研究的偏倚风险。数据从最终的研究列表中提取，并使用随机效应模型进行meta分析。汇总估计值采用森林图，发表偏倚采用漏斗图。对患有精神和身体残疾的人的糖尿病患病率进行亚组分析。结果:共筛选出771篇论文。其中740篇被排除，31篇纳入全文综述。最后，meta分析纳入了12项研究。2型糖尿病在残疾人中的患病率为12.8%(95%可信区间[CI]: 8.8%-16.8%)。这些研究显示了广泛的异质性。漏斗图未显示任何发表偏倚。亚组分析显示，2型糖尿病在精神残疾者中的患病率为14.0% (95% CI: 9%-18.9%)，而在其他形式身体残疾者中的患病率为10.6% (95% CI: 3.6%-17.6%)。结论:残疾人中2型糖尿病患病率较高。东南亚地区需要对残疾人中2型糖尿病的流行情况进行良好的系统研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Current medical issues

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