Verification of doses to PTV and OAR and 2D dose distribution in IMRT for 7 accelerators in Sichuan province

Q4 Medicine
Chunyong Yang, Yuanyuan Zhou, Xingjiang Cao, Xiang Du, S. Luo, Xian Xue, Zhi-jian He, Jin Wang
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Abstract

Objective To use TLDs and radiochromic films to verify the prescribed doses to both planned target volume (PTV) and organ at risk (OAR) and the 2D dose distribution in IMRT. Methods Eight accelerators of different models were selected in Henan province. The polystyrene phantom provided by IAEA was scanned using CT scanners and then the scanned images were transmitted to treatment planning system (TPS) for prescribing respectively the doses to PTV and OAR. IMRT was performed with phantom exposed to a 6 MV X-rays. The irradiated TLDs and films were delivered for measurement and estimation at Secondary Standard Dosimetry Laboratory at National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention. Results According to IAEA requirements, the relative deviations of the TLD-measured and TPS-planned values were within ±7.0% for the prescribed doses to PTV and OAR. The measured results for PTV have shown that the relative deviation of TLD-measured and TPS-planned values were within -0.3% to 6.9% for 8 accelerators, all consistent with the IAEA requirements. For OAR, the relative deviations of TLD-measured and TPS-planned were within -7.0% to 0.3% for 6 accelerators, consistent with the requirements, whereas those for other 2 accelerators were within -10.8% to -8.4%, not up to the requirements. IAEA required that, for 2D dose distribution, the pass rate of 3 mm/3% be ≥90%. The measured values for 7 accelerators were from 90.2% to 99.9%, consistent with the requirements, whereas that for another one was 70.0%, not meeting the requirement. Conclusions The method to verify, using radiochromic film and TLD, the prescribed doses to PTV and OAR and the pass rate of 2D dose distribution is simple and reliable. It is an important step to implement quality control for IMRT and can provide effective support for medical or third-party service institution to verify clinically prescribed dose. Key words: Intensity modulated radiation therapy; Radiochromic film; Planned target volume; Organ at risk; Two-dimensional dose distribution
四川省7个加速器IMRT中PTV和OAR剂量及2D剂量分布的验证
目的利用TLDs和放射显色膜验证IMRT中计划靶体积(PTV)和危险器官(OAR)的处方剂量和二维剂量分布。方法选取河南省8种不同型号的加速器。利用CT扫描仪对IAEA提供的聚苯乙烯体进行扫描,然后将扫描图像传输到治疗计划系统(TPS),分别对PTV和OAR进行处方剂量。幻影暴露于6 MV x射线下进行IMRT。辐照后的tld和薄膜送到中国疾病预防控制中心辐射防护所二级标准剂量测定实验室进行测量和估计。结果在规定剂量下,tld测定值与tps计划值对PTV和OAR的相对偏差在±7.0%以内,符合IAEA要求。PTV的测量结果表明,8个加速器的tld测量值与tps计划值的相对偏差在-0.3% ~ 6.9%之间,均符合IAEA要求。对于OAR, 6种加速器的tld测量值与tps计划值的相对偏差在-7.0% ~ 0.3%之间,符合要求,而另外2种加速器的tld测量值在-10.8% ~ -8.4%之间,不符合要求。国际原子能机构要求,对于二维剂量分配,3mm /3%的合格率≥90%。7个加速器的实测值在90.2% ~ 99.9%之间,符合要求,1个加速器的实测值为70.0%,不符合要求。结论采用放射显色膜法和TLD法对PTV和OAR的处方剂量及二维剂量分布的通过率进行验证,方法简单可靠。是IMRT实施质量控制的重要环节,可为医疗机构或第三方服务机构临床处方剂量验证提供有效支持。关键词:调强放疗;Radiochromic电影;计划目标量;有危险的器官;二维剂量分布
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来源期刊
中华放射医学与防护杂志
中华放射医学与防护杂志 Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
0.60
自引率
0.00%
发文量
6377
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