The Gabapentoids Conundrum: “Mind the Gabs”

IF 0.7 Q4 PSYCHOLOGY, EDUCATIONAL

Journal of Psychological and Educational Research Pub Date : 2019-09-04 DOI:10.33140/jepr.01.01.02

Ahmed. Y. Ali, Hamad Al Ghaferi, Abuelgasim Elrasheed

引用次数: 0

Abstract

Concerns about two Gabapentoids namely Gabapentin and Pregabalin have been raised for years. Both were introduced as anti-epileptic agents before finding a myriad of indications, not without controversy. Experts are divided about their safety; one camp defends their use the other flagging incidents of diversion, reports of abuse cases of overdosing and even mortality. This article presents alarming Middle Eastern example of a wave of Gabapentoids abuse, mostly Pregabalin, among patients seeking treatment at the National Rehabilitation Center, Abu Dhabiand UAE. It also provides an overview of indications, side effects, evidence for and against abuse and misuse potential, laboratory tests, all within the context of a substance use disorder rehabilitation service.

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Gabapentoids难题:“注意Gabs”

对加巴喷丁和普瑞巴林这两种加巴喷丁类药物的担忧已持续多年。在发现大量的适应症之前，这两种药物都被作为抗癫痫药物引入，并不是没有争议。专家们对它们的安全性存在分歧;一个阵营为他们的使用辩护，而另一个阵营则在不断强调转移注意力、滥用药物甚至死亡的报道。这篇文章提出了一个令人担忧的中东例子，即在阿联酋阿布扎比国家康复中心寻求治疗的患者中滥用加巴喷丁类药物，主要是普瑞巴林。它还概述了药物使用障碍康复服务范围内的适应症、副作用、支持和反对滥用和误用可能性的证据、实验室测试。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Psychological and Educational Research PSYCHOLOGY, EDUCATIONAL-

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： Journal of Psychological and Educational Research is a scientific review, appearing biannually, which publishes scientific materials belonging to all the fields of psychology. The emphasis falls on empirical studies, but it may include reviews, theoretical or methodological papers in psychology. Empirical papers with a strong theoretical framework and/or models of computational parameters are particularly encouraged. Theoretical papers of scholarly substance on abnormality may be appropriate if they advance understanding of a specific issue directly relevant to psychology and fall within the length restrictions of a regular (not extended) article. As a journal that focuses on researches within a quantitative, scientific remit, Journal of Psychological and Educational Research places particular emphasis on the publishing of high-quality empirical reports based on experimental and behavioural studies