Artrite reumatoide e qualidade do sono

Q Medicine
Ana Claudia Janiszewski Goes, Larissa Aparecida Busatto Reis, Marilia Barreto G. Silva, Barbara Stadler Kahlow, Thelma L. Skare
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引用次数: 51

Abstract

Background

Sleep disturbances are common in rheumatoid arthritis (RA) patients and contribute to loss of life quality.

Objective

To study associations of sleep quality with pain, depression and disease activity in RA.

Methods

This is a transversal observational study of 112 RA patients submitted to measurement of DAS‐28, Epworth scale for daily sleepiness, index of sleep quality by Pittsburg index, risk of sleep apnea by the Berlin questionnaire and degree of depression by the CES‐D (Center for Epidemiologic Studies Depression scale) questionnaire. We also collected epidemiological, clinical, serological and treatment data.

Results

Only 18.5% of RA patients had sleep of good quality. In univariate analysis a bad sleep measured by Pittsburg index was associated with daily doses of prednisone (p = 0.03), DAS‐28 (p = 0.01), CES‐D (p = 0.0005) and showed a tendency to be associated with Berlin sleep apnea questionnaire (p = 0.06). In multivariate analysis only depression (p = 0.008) and Berlin sleep apnea questionnaire (p = 0.004) kept this association.

Conclusions

Most of RA patients do not have a good sleep quality. Depression and risk of sleep apnea are independently associated with sleep impairment.

类风湿性关节炎与睡眠质量
背景睡眠障碍在类风湿性关节炎(RA)患者中很常见,并导致生活质量下降。目的研究RA患者睡眠质量与疼痛、抑郁和疾病活动的关系。方法这是一项针对112名RA患者的横向观察性研究,他们接受了DAS‐28、Epworth日常嗜睡量表、Pittsburg指数睡眠质量指数、Berlin问卷睡眠呼吸暂停风险和CES‐D(流行病学研究中心抑郁量表)问卷抑郁程度的测量。我们还收集了流行病学、临床、血清学和治疗数据。结果只有18.5%的RA患者睡眠质量良好。在单变量分析中,Pittsburg指数测量的不良睡眠与泼尼松(p=0.03)、DAS‐28(p=0.001)、CES‐D(p=0.0005)的日剂量相关,并显示出与柏林睡眠呼吸暂停问卷(p=0.06)相关的趋势。在多变量分析中只有抑郁症(p=0.008)和柏林睡眠呼吸中止问卷(p=0.004)保持这种相关性。结论大多数RA患者睡眠质量不好。抑郁症和睡眠呼吸暂停风险与睡眠障碍独立相关。
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来源期刊
CiteScore
0.82
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: RBR nasceu da necessidade de se criar um órgão oficial da SBR que pudesse divulgar a produção científica dos reumatologistas brasileiros. O primeiro número foi publicado em setembro de 1957. A partir do volume 18 (1978), passou a seis números, com periodicidade atual. A RBR, em sua trajetória, tem sido objeto de constantes mudanças, sempre visando ao seu aprimoramento e revitalização, tanto em sua apresentação como em seu conteúdo.
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