André Luiz Peixoto Figueiredo , Liliane Lins , Ana Carolina Cattony , Antônio Fernando Pereira Falcão
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引用次数: 10
激光治疗口腔粘膜炎的荟萃分析
目的对激光治疗(LT)预防肿瘤治疗患者口腔粘膜炎(OM)的有效性进行系统回顾和荟萃分析。方法在MEDLINE、LILACS和Cochrane数据库中使用关键词“激光治疗”和“口腔粘膜炎”进行检索,以进行系统综述和荟萃分析。纳入的病例对照研究进行比值比(OR)分析,其统计计算的截止值为OM≥3级。使用BioEstat程序5.0版,使用DerSimonian Laird的随机效应统计分析进行计算。结果本系统综述包括12项研究;对其中7例患者的荟萃分析表明,接受肿瘤治疗的患者的LT在预防OM≥3级方面的有效性是未接受激光治疗的患者约10倍(OR:9.5281;95%CI:1.447-52.0354;p=0.0093),需要更大的样本量来更好地评估LT对OM≥3级的预防效果。
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